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Allergen Immunotherapy

Purpose

Your individualized course of allergy shots (immunotherapy) is designed to decrease your allergic sensitivities. The vast majority of allergic patients (80-90%) will experience substantial reductions in their symptoms over time (months to years). Many also reduce or eliminate the need for other medications. Together with avoidance of offending allergens and medication allergy shots represent one of the recommended treatments for allergic rhinitis, allergic conjunctivitis, atopic dermatitis and asthma. Allergy shots are not useful for food/drug allergies or non-allergic conditions like infections.

Treatment Duration

The length of a treatment course varies on a case by case basis but in general a course requires 3 to 5 years of maintenance treatment for completion. Initially there is a build-up phase where the injections are given more frequently but as the High Dose, or maintenance dose, is reached the frequency of injections may be adjusted. The total duration of therapy can vary considerably from patient to patient. During your treatment you will be re-evaluated frequently by your physician. These visits will occur at least annually.

Schedule of Administration

Your series of injections begins at a low dose selected by your physician based on your skin test results and history. Over time the shots build gradually until you reach your High Dose. This High Dose is called the maintenance dose and you will stay on it for the duration of your treatment course unless it is changed by your physician. Maintenance therapy can be continued if you are pregnant BUT notify your OAAC physician when you become pregnant.

The build-up phase of the allergy shots can occur in different formats. Your physician will help you decide which is right for you. Most common is the weekly building schedule. Various accelerated schedules include: 2 or 3 time a week shots, clusters of several shots given on the same day and finally RUSH therapy where many injections are given on one day and then weekly shots follow until you are at your High Dose. RUSH therapy is associated with significantly more side effects (see below) and is not for every patient. However, it does bring you to the High Dose level in a month rather than slowly over many months. This is an advantage for some patients.

Safety

All allergy shots carry some risks for severe anaphylactic reactions. Therefore the injections need to be administered in a medical facility under medical supervision on a regular basis. Weekly or twice weekly shots from our clinic carry a risk of anaphylaxis of 0.015 to 0.02% of injections compared to nationally published risks of 0.1 to 0.3% of injections. RUSH therapy carries a nationally published risk of almost 40% of shots whereas our RUSH risk is closer to 10% of injections. This marked increase in risk however makes RUSH therapy unacceptable for many patients.

Recent News

Grass Pollen Allergy
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Grass Pollen Allergy

If the smells of freshly cut lawns make you sneeze, you may have a grass pollen allergy. Grass pollen is a common cause of allergy. Every spring and summer, plants release tiny pollen grains to fertilize same species plants. Grass pollen can trigger allergic reactions.

If you are experiencing these symptoms, grass pollen may be the trigger:

  • Runny nose
  • Sneezing
  • Itchy nose, eyes, ears and mouth
  • Stuffy nose (nasal congestion)
  • Red and watery eyes
  • Swelling round the eyes

 Since grass pollen grains may not be visible to the eye, your body may react even to tiny amounts of pollen in the air. With Oklahoma’s strong winds, pollen is distributed across the state.

Also known as hay fever, allergists refer to pollen allergy as seasonal allergic rhinitis.

What grasses cause allergy symptoms?

Fortunately, only a few grasses cause allergic symptoms. Where you live also plays a factor in grass allergy.

The most common grasses causing allergies are:

  • Bermuda
  • Johnson
  • Kentucky
  • Orchard
  • Rye
  • Sweet Vernal
  • Timothy

Living in Oklahoma, grass can pollinate through most of the year. Tiny, light and dry – grass pollen grains can travel for hundreds of miles.

“The first step is to get tested and diagnosed,” said OAAC Allergist Dr. Bret Haymore. “Once your allergist knows what specific allergens causing your symptoms, then we can work with you to create a treatment plan.”

Options for treatment include over-the-counter medicines, liquids or nasal sprays and prescription pills (also known as antihistamines, decongestants and nasal steroids). These can help reduce or prevent grass allergy symptoms.

“Grass allergy pollen medicines work best when you start taking them before pollen season begins,” said Dr. Haymore. “This will allow the medicines to prevent your body from releasing histamine and other chemicals that cause your symptoms.”

Another option if those medicines are no longer helping, may be immunotherapy or allergy shots. There are two types of grass allergy immunotherapy – allergy shots and allergy tablets. 

“Immunotherapy is a long-term course of treatment that can reduce or even prevent the severity of allergic reactions,” he said. “Allergy shots usually take a one-to-three-year commitment and can modify the body’s immune response to allergens.”

Allergy shots or subcutaneous immunotherapy (SCIT) are given at the OAAC clinics. Patients are monitored for any type of reaction to the shot. Most common side effects include local reactions at the injection site – redness, itching, swelling, tenderness, and pain. Less common reactions may include generalized redness, hives, itching, swelling, wheezing and low blood pressure.

Allergy tablets or sublingual immunotherapy (SLIT) can be done at home. This therapy involves placing a tablet containing the allergen under the tongue for one to two minutes and then swallowing it. Treatment must begin before grass allergy season and continues throughout grass allergy season. Taking the daily tablets may reduce grass allergy symptoms. There can be some side effects, and some can be serious. Please discuss with SLIT therapy with your OAAC provider about treatment options.

The post Grass Pollen Allergy appeared first on Oklahoma Allergy and Asthma Clinic.

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