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Allergen Immunotherapy

Purpose

Your individualized course of allergy shots (immunotherapy) is designed to decrease your allergic sensitivities. The vast majority of allergic patients (80-90%) will experience substantial reductions in their symptoms over time (months to years). Many also reduce or eliminate the need for other medications. Together with avoidance of offending allergens and medication allergy shots represent one of the recommended treatments for allergic rhinitis, allergic conjunctivitis, atopic dermatitis and asthma. Allergy shots are not useful for food/drug allergies or non-allergic conditions like infections.

Treatment Duration

The length of a treatment course varies on a case by case basis but in general a course requires 3 to 5 years of maintenance treatment for completion. Initially there is a build-up phase where the injections are given more frequently but as the High Dose, or maintenance dose, is reached the frequency of injections may be adjusted. The total duration of therapy can vary considerably from patient to patient. During your treatment you will be re-evaluated frequently by your physician. These visits will occur at least annually.

Schedule of Administration

Your series of injections begins at a low dose selected by your physician based on your skin test results and history. Over time the shots build gradually until you reach your High Dose. This High Dose is called the maintenance dose and you will stay on it for the duration of your treatment course unless it is changed by your physician. Maintenance therapy can be continued if you are pregnant BUT notify your OAAC physician when you become pregnant.

The build-up phase of the allergy shots can occur in different formats. Your physician will help you decide which is right for you. Most common is the weekly building schedule. Various accelerated schedules include: 2 or 3 time a week shots, clusters of several shots given on the same day and finally RUSH therapy where many injections are given on one day and then weekly shots follow until you are at your High Dose. RUSH therapy is associated with significantly more side effects (see below) and is not for every patient. However, it does bring you to the High Dose level in a month rather than slowly over many months. This is an advantage for some patients.

Safety

All allergy shots carry some risks for severe anaphylactic reactions. Therefore the injections need to be administered in a medical facility under medical supervision on a regular basis. Weekly or twice weekly shots from our clinic carry a risk of anaphylaxis of 0.015 to 0.02% of injections compared to nationally published risks of 0.1 to 0.3% of injections. RUSH therapy carries a nationally published risk of almost 40% of shots whereas our RUSH risk is closer to 10% of injections. This marked increase in risk however makes RUSH therapy unacceptable for many patients.

Recent News

Lone Star Tick Bite – Alpha Gal
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Lone Star Tick Bite – Alpha Gal

An article in Allergic Living magazine focused on the Alpha-gal allergy – an allergic disease caused by the Lone Star tick bite. However, you may be surprised at how many people are living with this disease that affects everything they eat. Those with Alpha-gal can’t eat mammalian meat – beef, pork, lamb, rabbit, etc. Turns out best-selling author, John Grisham, suffers from this disease, according to the article.

Grisham who keeps meticulous notes, found out in 2012, after working with his allergist on his case of his skin feeling like it was on fire. His hives were actually a reaction to eating mammalian meat.

According to the article, Grisham has become an old pro at managing his meat-restricted diet with the help of his wife, Renee, who also has the disease. He has learned to savor healthy alternatives to beef and pork although he regularly gets red meat cravings.

He and Renee live near Charlottesville, Virginia, while beautiful and historic, is a favorite habitat to the Lone Star tick.

There is no treatment for red meat allergy beyond avoiding the consumption of red meat and in some cases, dairy and gelatin. There is a chance this allergy may resolve over time if the affected person prevents getting another tick bite. As research advances, there is hope a better treatment of red meat allergy will be found.

“With our mild winter, ticks are out, and ready to bite,” says OAAC Board-Certified Allergist Dr. Laura Chong. “Warmer weather means we are starting to spend more time outside. Be sure and take your tick prevention precautions for you and your pets that carry them inside your house.”

 

The post Lone Star Tick Bite – Alpha Gal appeared first on Oklahoma Allergy and Asthma Clinic.

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